Sciensano supports Belgian and European health policy by innovative scientific research, surveillance and expert advice. Our 800 employees collaborate in more than 100 scientific projects, financed by governmants, Belgian or international partners and stakeholders. More information on current and future projects can be found at https://www.sciensano.be.
As a PhD student you will work exclusively on the QMED project within the department of medicines and healthcare products. Our department is part of the official medicine control laboratory (OMCL) and recognized as a national reference for the quality control of medicines and cosmetics. With this project the department aims to expand into the quality control of medical devices such as dental acrylates, glucose sensors, wound care products, stoma care products and reusable surgical materials.
The QMED project will focus on two distinct toxicological endpoints, being allergic reactions and fever inducing contaminations also known as pyrogens. In the first part, products will be screened for potential allergens using liquid and gas chromatography coupled to mass spectrometry. Afterwards the identified compounds will be evaluated using in vitro and in silico toxicological tools. In the second part of the project, we will investigate reusable medical devices for their potential contamination with pyrogens. This evaluation will also be based upon an in vitro technique using human monocytes. Devices testing positive will undergo further evaluation to identify the root cause of the contamination.
You work as coordinating scientist for the QMED project within the medicines team of Sciensano.
You will work in close collaboration with the internal services of Epidemiology and public health, quality of laboratories and infectious diseases in humans.
You collaborate intensely with the external partners of the federal agency for medicines and health products and the “Vrije universiteit Brussel” (VUB).
You are responsible for following up the most recent developments in the field, discuss with national and international stakeholders, participate actively in national and international meetings and conferences and present your findings in peer-reviewed journals.
Master of biological, biomedical, chemistry or pharmaceutical sciences, or equivalent.
Technical competences (theoretical or practical knowledge): analytical chemistry (especially liquid chromatography and mass spectrometry); in vitro toxicological test based upon cell cultures and molecular biological assays; insights in the regulatory landscape of the medical devices is an asset.
Generic competences: result driven; problem solving mindset; works well under pressure; eager to learn; good communication skills (written and oral); team player
Languages: excellent knowledge of English; Dutch or French
4-year doctoral scholarship
Research project supported by senior scientists of Sciensano, in the field of public health
Net monthly compensation of +/- 1800 euro
100% reimbursement of cost for public transportation, meal vouchers
Start-up scheduled for January 2022
Apply on our website: https://www.sciensano.be/en/working-sciensano/my-employment-opportunities !
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